2023年5月31日 星期三

Arexvy (respiratory syncytial virus vaccine, adjuvanted) for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV)

GSK plc (LSE/NYSE: GSK) today announced that the US Food and Drug Administration (FDA) has approved Arexvy (respiratory syncytial virus vaccine, adjuvanted) for the prevention of lower respiratory tract disease (LRTD) caused by respiratory syncytial virus (RSV) in individuals 60 years of age and older.

GSK plc(倫敦證券交易所/紐約證券交易所代碼:GSK)今天宣布,美國食品藥品監督管理局(FDA)已批准 Arexvy(呼吸道合胞病毒疫苗,佐劑)用於預防由呼吸道合胞病毒(RSV)引起的下呼吸道疾病(LRTD) ) 在 60 歲及以上的個體中.

formidable, revamp, steady force, becquerel, motherhood, Stand someone/something in good stead, formidable stature in the culture has shown a few cracks


Donald Trump’s political machine has started the year with more than $100mn, reinforcing his status as the Republican party’s most formidable fundraiser as he toys with another run for the White House in 2024
https://on.ft.com/3IUKm2R

Guitarist and singer-songwriter Jimi Hendrix was born on this day in 1942. His talent was formidable, his ascent to fame swift


Stacy Schiff penetrates an ancient thicket of personalities and propaganda to reconstruct the Macedonian-Egyptian queen Cleopatra in all her ambition, audacity and formidable intelligence.





Illustration by Javier Jaén Benavides



Family Way
By JUDITH WARNER



Two new books examine the current culture of motherhood: one bemoaning it and the other suggesting what might be done to improve the balance of work and family demands.

Up Front: Judith Warner

'Making Babies'
By JUDITH NEWMAN


The novelist Anne Enright offers an unsentimental look at the essential condition of motherhood: absurdity.





Farm ministry effort to stop 'becquerel war' draws fire

BY MASAKO FURUKAWA ASAHI SHIMBUN WEEKLY AERA
2012/05/08
photoA shop near JR Shinbashi Station in Tokyo sells produce harvested in Fukushima Prefecture with labels saying radioactive cesium is lower than 10 becquerels. (Asahi Shimbun file photo)
On April 23, a few days before the start of Japan's Golden Week holidays, phones at the farm ministry's Food Industry Affairs Bureau were ringing off the hook.



Angela Merkel: From shy physicist to re-elected stateswoman

Elected for a second term at the helm of Europe's largest economy, Angela
Merkel is regarded by voters as a steady force in a time of crisis and a
formidable presence on the world stage.


Wartime Soldier, Conflicted Mom

By LIZETTE ALVAREZ
The U.S. military has in large part adapted to women fighting successfully alongside men. Motherhood, though, poses a more formidable challenge.

Pierre Curie and Marie Sklodowska wed on this date in 1895. The two became the formidable scientific team that discovered polonium and radium. In 1903, they shared the Nobel Prize in Physics with Professor Henri Becquerel for their discovery of radioactivity.

Google's biggest threat may not be Microsoft (MSFT) or Yahoo! (YHOO).
No, one of the most formidable challenges facing Google (GOOG) is likely sitting in your pocket or purse. It's your cell phone, and it will put added pressure on Google and other Internet companies to revamp the way they handle online marketing.



to be useful or helpful to someone or something His language skills will stand him in good stead when he is traveling.


formidable
ˈfɔːmɪdəb(ə)l,fɔːˈmɪd-/
adjective
  1. inspiring fear or respect through being impressively large, powerful, intense, or capable.
    "a formidable opponent"

formidable 
adjective ━━ a. 手に負えない, 恐るべき; 抜群の.
causing you to have fear or respect for something or someone because they are impressive, powerful or difficult:
a formidable obstacle/task
a formidable adversary/enemy/opponent
a formidable intellect
DISAPPROVING the director and his formidable wife





revamp
(rē-vămp') pronunciation
tr.v., -vamped, -vamp·ing, -vamps.
  1. To patch up or restore; renovate.
  2. To revise or reconstruct (a manuscript, for example).
  3. To vamp (a shoe) anew.
n.
The act or an instance of revamping; a complete reorganization or revision.

revampment re·vamp'ment n.

 becquerel

(bĕ-krĕl', bĕk'ə-rĕl') pronunciation
n. (Abbr. Bq)
The International System unit of radioactivity, equal to one nuclear decay or other nuclear transformation per second.

[After Antoine Henri BECQUEREL.]

sassy, dogsled ride, mockery, impudent, ‘the Hogwarts of Fashion’





He kicks off his speech with a pretty solid joke.

"For those of you traveling with your children... why?"
TIME.COM



The ruling "tandem" make a mockery of Russian democracy(88)



To that end, Mr. Cameron set about decontaminating the Tory brand. Central to that mission were forays into two areas of political terrain previously deemed forbidden zones. First, he signaled comfort with gay rights, ditching the party’s previous support for laws restricting sexual equality. Second, he championed environmentalism. He may have endured news media mockery when he took a dogsled ride to inspect a Norwegian glacier in 2006, but it did the trick, confirming that the Tories were changing.




impudent Pronunciation (adjective) Improperly forward or bold.
Synonyms:overbold, sassy, saucy, impertinent, smart, wise, fresh
Usage:Mind your own business, you impudent young rascal, and I'll mind mine.


Hogwarts School of Witchcraft and Wizardry, a school for learning magic in J.K. Rowling's Harry Potter series. quotations ▼ Any institution similar in field, appearance, or oddity.

sassy

Line breaks: sassy
Pronunciation: /ˈsasi 
  
/

ADJECTIVE (sassiersassiest)

INFORMAL
  • Lively, bold, and full of spirit; cheeky:Toni was smart and sassy and liked to pretend she was a hard nut

Derivatives

sassily

ADVERB

sassiness

NOUN

Origin

mid 19th century: variant of saucy.

mockery

(mŏk'ə-rē) pronunciation

n., pl. -ies.
  1. Scornfully contemptuous ridicule; derision.
  2. A specific act of ridicule or derision.
  3. An object of scorn or ridicule: made a mockery of the rules.
  4. A false, derisive, or impudent imitation: The trial was a mockery of justice.
  5. Something ludicrously futile or unsuitable: The few packages of food seemed a mockery in the face of such enormous destitution.

hard master, slug-fest, hard-hitting, trenchant, preposterous, rematch/replay, Sinterklaas, jocular, pratfall

In Iowa, DeSantis Signals the Start of a Slugfest With Trump

After absorbing months of attacks from former President Trump, Gov. Ron DeSantis of Florida is beginning to fire back — but carefully.




The lack of a handshake was far from the way in which the Cleveland debate broke the normal conventions of civility.

USATODAY.COM
'Will you shut up, man?' 5 takeaways from the slugfest between Donald Trump and Joe Biden in Cleveland
At Tuesday's debate, Donald Trump repeatedly interrupted Joe





"Happiness is a hard master–particularly other people's happiness. A much harder master, if one isn't conditioned to accept it unquestioningly, than truth."
--The Controller from BRAVE NEW WORLD by Aldous Huxley


“In this country we think of Holland as a very advanced nation, with advanced social principles.” Yet tomorrow, on the Dutch festival of Sinterklaas, many will fail to see a problem with dressing up like thishttp://econ.st/1I4oluG
Who, us? Racist? THE Dutch festival of Sinterklaas on December 5th, the country’s most important children’s holiday, is turning into an annual slugfest of racial...
ECON.ST

The Slugfest in the Executive Suite
The popularity, and value, of mixed martial arts on television has left two media giants in a battle over the future of the sport.


Barney Rosset, 1922-2012

Defied Censors, Making Racy a Literary Staple

By DOUGLAS MARTIN
Barney Rosset, who helped change the course of publishing in the United States, bringing masters like Samuel Beckett to Americans' attention, and who won celebrated First Amendment slugfests against censorship, died on Tuesday.

Chekhov's Slugfest, With Pratfalls

By BEN BRANTLEY
Cate Blanchett, Richard Roxburgh and Hugo Weaving star in the Sydney Theater Company revival of "Uncle Vanya" at the Kennedy Center in Washington.



Literary Slug Fests (August 17, 1937)
A jocular Times Editorial suggested that a Hemingway-Eastman rematch "really ought to be staged in Carnegie Hall for the benefit of the Nobel Peace Fund or something."


  1. Sinterklaas - Wikipedia, the free encyclopedia

    en.wikipedia.org/wiki/Sinterklaas

    Sinterklaas is celebrated annually with the giving of gifts on the night before Saint Nicholas Day (5 December) in the Netherlands and on the morning of 6 ...
When CBS's 60 Minutes first aired in 1968, no one expected it to become one of network television's most popular programs ever. Yet 60 Minutes became the role model that all other investigative television programs have sought to emulate, and its clicking stopwatch became one of TV's most recognized images. In the beginning, there were two reporters: Harry Reasoner and Mike Wallace. Others, including Morley SaferEd BradleyDan Rather and Lesley Stahl, helped to make 60 Minutes the most-watched newsmagazine in TV history. Wallace, famous for his aggressive, hard-hitting interviews — and still an occasional contributor to the show — turns 90 today.
The seemingly inevitable prospect of Donald J. Trump becoming the Republican candidate is terrifying. But it does at least offer the prospect of some angry, hard-hitting art.

The best political art is always viciously negative. And the monsterly…
THEGUARDIAN.COM|由 JONATHAN JONES 上傳




News - Health - Delivering a verdict: Ian Kennedy . Last updated: 17 Jul 2001
Reith lectures As early as 1980, he delivered a series of Reith lectures, broadcast on the BBC, which contained trenchant criticism of way that doctors regulate themselves.

on Page 16: "Paul Ricoeur so trenchantly puts it, Freud adhered at times to a nineteenth-century physicalist model that frowned on intentional-state explanations.23 So it is part of our heritage ... "


Obama’s Ads in Key States Go on Attack 

By JIM RUTENBERG
Barack Obama has started a hard-hitting ad campaign against John McCain in vital states, painting Mr. McCain as disconnected from middle-class struggles.




STYLE

One Comic, Twice the Laughs
Two comic personalities seemed to coexist within George Carlin during his preposterously long and fertile career. Both Carlins could amuse and both could be trenchant, but each came at his target from wildly different angles.
(By Paul Farhi, The Washington Post)


hard
Not showing sympathy or affection; strict:he can be such a hard taskmaster

trench・ant


  
━━ a. 刺すような, 痛烈な ((ことば,批評など)); はっきりした (in ~ outline くっきりと).


WordNet: preposterous
The adjective has one meaning:
Meaning #1: completely devoid of wisdom or good sense
Synonyms: absurdderisorylaughableludicrousnonsensicalridiculous


hard-hitting

(hārd'hĭt'ĭng)

adj.
Effective; forceful.

slugfest - a fight with bare fists 

slug-fest
noun, US

hard-hitting contest, esp. in boxing or baseball. (1916 —) .


WordNet: hard-hitting
Note: click on a word meaning below to see its connections and related words.
The adjective has 2 meanings:
Meaning #1: characterized by or full of force and vigor
Synonym: trenchant
Meaning #2: aggressively and persistently persuasive
Synonym: high-pressure
adjective
  1. uncompromisingly direct and honest, especially in revealing unpalatable facts.
    "a hard-hitting anti-fox-hunting poster"

hard-hit·ting (hrdhtng)
adj.
Effective; forceful.
adj
uncompromising; tough
a hard-hitting report on urban deprivation



trenchant
adjective SLIGHTLY FORMAL
severe, expressing strong criticism or forceful opinions:
His most trenchant criticism is reserved for the party leader, whom he describes as 'the most incompetent and ineffectual the party has known.'
Dorothy Parker's writing is characterized by a trenchant wit and sophistication.



Arizona Daily Star Powers gave up four runs on seven hits, a contrast from the 33-hit slugfest of Friday night (1979).





slugfest
noun
INFORMALNORTH AMERICAN
  1. a tough and challenging contest, especially in sports such as boxing and baseball.
    "the fight brought back memories of the classic 1976 Lyle-Foreman slugfest"
slug-fest
[From slug verb, to hit + fest noun, special occasion, festival.]

[slʌ'gfèst] [名]((主に米略式))(ボクシングの)激しい打ち合い, 好ファイト, (野球の)打撃戦, 乱打戦.

The noun rematch has one meaning:
Meaning #1: something (especially a game) that is played again
Synonym: replay

jocular
(jŏk'yə-lər) pronunciation
adj.
  1. Characterized by joking.
  2. Given to joking.
[Latin ioculāris, droll, from ioculus, diminutive of iocus, joke.]
jocularity joc'u·lar'i·ty (-lăr'ĭ-tē) n.
jocularly joc'u·lar·ly adv.
[形]((形式))こっけいな, ひょうきんな, 浮かれた, ユーモラスな
a jocular fellow
おもしろいやつ.
[ラテン語joculār (jocus冗談+-ulus指小辞+-AR=小さな冗談の). △JOKE




pratfall
(prăt'fôl') pronunciation
n.
  1. A fall on the buttocks.
  2. A humiliating error, failure, or defeat: "His characters not only survive their snarled problems and pratfalls but learn from their experiences" (Joyce Carol Oates).