If something goes against the grain, you would not usually do it because it would be unusual or morally wrong:
These days it goes against the grain to show respect for authority.
MERGERS & ACQUISITIONS
A report by The New York Times that Warren E. Buffett is in talks to buy as much as 20 percent of Bear Stearns has raised the specter of the investor's 1987 deal to take a 12 percent stake in Salomon Brothers. But TheStreet.com suggested that a Bear investment would go against the grain for Buffett.
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